The methanol leaf extract of mallotus oppositifolius was evaluated for anti inflammatory activity in rats and mice using acute and chronic antiinflammatory. Newman osafo, in medicinal plant research in africa, 20. Is a shrub that is commonly found in drier types of forest secondary growth throughout the west, african region. Pdf antifungal property and phytochemical screening of the crude. Please note that this is a trial program and may end. A new acylphloroglucinol with a novel architecture including an unprecedented dearomatic dibenzofuran core, named callistemenonone a 1, was isolated from the leaves of callistemon viminalis. Deconstruction of an african folk medicine uncovers a. Dpph scavenging activity of mallotus oppositifolius. Scientific evidence of plant with a rapidonset and sustained. Mallotus e um genero botanico pertencente a familia euphorbiaceae algumas plantas deste genero sao encontrados na africa tropical e madagascar. Bioassayguided fractionation of an ethanol extract of the leaves and inflorescence of mallotus oppositifolius collected in madagascar led to the isolation of the two new bioactive dimeric phloroglucinols mallotojaponins b 1 and c 2, together with the known mallotophenone 3. Structures were elucidated by comprehensive spectroscopic analyses and hrms data.
Notes the plants can range from almost completely glabrous to conspicuously hairy. Until now, the molecular mechanism was not completely understood. The chromatographic separation of the components of the acetone extract of mallotus philippensis fruits yielded five new phenolic compounds including two chalcones, 1 and 3, a functionalized phloroglucinol, 2, two flavanones, 4 and 5, and six known compounds. Antiinflammatory and antioxidant activities of mallotus. Evaluation of mallotus oppositifolius methanol leaf extract on the. Mallotus oppositifolius is an open shrub or a tree with elongated branches that can be curved, pendulous or ascending. At this time of the year you can see numberof butterflies on different flowers and number of birds on flowersfruits. The antifungal properties of aqueous and ethanol extracts of funtumia elastica and mallotus oppositifolius were carried out using the disc diffusion agar assay.
Mansonia kamerunica asosong mh dec feb forests tree with white flowers, sweet fruits attract bees 16 81. A shrub or small tree to m high, common in drier types of forest and in secondary regrowth throughout the region and widespread across tropical africa to madagascar. Identification and quantification of phytochemical. Pdf phytochemical and biological analysis of mallotus. An mallotus oppositifolius in nahilalakip ha genus nga mallotus, ngan familia nga euphorbiaceae. The procedures were carried out in triplicates and the mean used in computations. A maioria sao encontradas no leste e sudeste da asia e, desde a indomalasia ate a nova caledonia e fiji, norte e leste australiano.
The bole is around 10cm in diameter, usually branching from low down. Bluethroated barbet is on bullocks heart fruit annona reticulata. Jan 16, 2015 mallotus oppositifolius is a tropical plant used to treat many medical conditions in africa. Mallotus philippensis is a plant in the spurge family. Mallopenins ae, antibacterial phenolic derivatives from the. Evaluation of mallotus oppositifolius methanol leaf extract. African journal of biotechnology 2 the rats were fasted overnight before experimentation but were allowed free access to water. Pdf phytochemical studies and antioxidant properties of. Euphorbiaceae is folklorically used to treat diabetic conditions in some parts of nigeria therefore the study, to investigate the extract of the leaves for activities on hyperglycaemia, lipid peroxidation, and increased cholesterol levels in vivo in alloxan diabetic rats as well as its potential antioxidant activity in. Mallotus is a genus of the spurge family euphorbiaceae first described as a genus in 1790. Researchers discover molecular mechanisms of an african. Mallotus oppositifolius mallotus oppositifolius x 3k jpg medias. Bioactive phloroglucinols from mallotus oppositifolius.
Mallotus oppositifolius is used in ghana for cns disorders but very little. The antioxidant activity was done in vitro using ferric reducing antioxidant power frap and 1,1diphenyl2hydrazyl. In west africa it is grown in and around cassava fields to reduce the impact of animals that feed on the leaves, as they prefer mallotus oppositifolius leaves. Research article evaluation of mallotus oppositifolius. Mallotus oppositifolius is widely distributed and occurs from senegal east to ethiopia and south to angola and mozambique, and also in. Antiproliferative and antiplasmodial dimeric phloroglucinols from. Mallotus oppositifolius is a plant species in the genus mallotus found in africa and madagascar. The structures of the new compounds were determined on the basis of spectroscopic evidence, including their 1d. Pagka karon wala pay siak nga nalista ubos niini niya. Antiproliferative and antiplasmodial dimeric phloroglucinols. The total antioxidant activity of the mallotus oppositifolius mp extract was estimated by the ferric reducing antioxidant power frap assay and the 1,1diphenyl2picrylhydrazyl dpph photometric assay. The aqueous and ethanol extracts of the plant show antifungal properties, and anti parasitic activity against blastocystis hominis. Beeloving plants for honey food and agriculture organization. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs.
Here, we used pharmacological screening and electrophysiological analysis in combination with in silico docking and sitedirected mutagenesis to elucidate the effects of m. The identification of the phytochemicals in the sample was carried out using a qp2010 gas chromatography with thermal desorption system, td 20 coupled with mass spectroscopy. The plant is a common weed of ricefields in bendel state of nigeria 21. Antibacterial phloroglucinols derivatives from the leaves.
The herbal medicine, a leaf extract from the shrub mallotus oppositifolius, has been used across africa for centuries. All free radical scavenging assays were carried out in triplicates and the results shown in the figures represent a mean of the values obtained. Callistemenonone a, a novel dearomatic dibenzofurantype. Jun 26, 2019 mallotus oppositifolius can be coppiced and pollarded. Comparative morphological, anatomical and phytochemical studies on two species of euphorbiaceae m. This information is available free of charge via the internet at. An ethanol extract of mallotus oppositifolius geiseler mull. Mallopenins ae, antibacterial phenolic derivatives from. Page 26 26 insert cards all the way in to hear click. Enhancement of inhibitory neurotransmission and inhibition of. However, it must be distinguished from kamala meaning lotus in many indian languages, an unrelated plant, flower, and sometimes metonymic spiritual or artistic concept. Mallotus comprises about species, which all occur in mzllotus old world tropics, mainly in asia and oceania. From the ethnomedicinally used leaves of mallotus oppositifolius, four acylphloroglucinol derivatives, namely acronyculatin s u and mallotojaponin d 4 were isolated along with seven known compounds 511. Research article antidepressant effects of mallotus oppositifolius in acute murine models kennedyk.
Euphorbiaceae is folklorically used to treat diabetic conditions in some parts of nigeria therefore the study, to investigate the extract of. Absolute configurations were assigned by careful comparison of their specific optical rotation. Dmax user guides and product manuals press the sensor number and ent key. Introduction the cumulative effect of increased free radicals, especially reactive oxygen species ros and reactive nitrogen species rns is the cause of several chronical and degenerative diseases 14. Pdf antidepressant effects of mallotus oppositifolius in. Sep 01, 2016 read scientific evidence of plant with a rapidonset and sustained antidepressant effect in a chronic model of depression. Mallotus oppositifolius held a place in natural medicine fabricant and farnsworth, 2001. Article pdf available in biochemistry research international 20. Evaluation of mallotus oppositifolius methanol leaf. Pdf evaluation of mallotus oppositifolius methanol leaf extract on. These also show that trevia is embedded within mallotus but. Home archives vol 11 no 2 2018 articles comparative chemotaxonomic studies on sroti mallotus oppositifolius geiseler mull and velvet bush willow mallotus alternifolius merr.
Mallotus oppositifolius plant is known locally as kafar mutuwaa by hausas, ija by yorubas andnne okpo kirinya by igbos 5. Pdf on jul 1, 2012, fa kabran and others published. Mallotus oppositifolius is a shrub that is used traditionally to treat epilepsy, but its potential has not been scientifically validated. General information kamala is an evergreen tree, growing up to 25 metres tall. The kcnq1 gene belongs to a large family of genes that provide instructions for making potassium channels. All structured data from the file and property namespaces is available under the creative commons cc0 license. Gcms analysis for structural identification and bioactive. Access is allocated within two business days of purchase and lasts one year. A third of the global population relies heavily upon traditional or folk medicines, such as the african shrub mallotus oppositifolius. Research article antidepressant effects of mallotus. Despite the use of mallotus oppositifolius in treating psychiatric and affective disorders in ghana, there is no scientific data on its antidepressant effect. This article cites 44 articles, 10 of which you can access for free. These channels, which transport positively charged atoms ions of potassium out of cells, play key roles in a cells ability to generate and transmit electrical signals.
Deconstruction of an african folk medicine uncovers a novel. Evaluation of mallotus oppositifolius methanol leaf extract on the glycaemia and lipid peroxidation in. Aug 01, 2019 mallotus oppositifolius mallotus oppositifolius x 3k jpg medias. Free fulltext pdf articles from hundreds of disciplines, all in one place. Hydroalcoholic extract of leaves of mallotus oppositifolius moe, a plant used for cns conditions in ghana, was investigated for acute antidepressant effects in the forced swimming. Apr 18, 2015 this page was last edited on 18 april 2015, at 20.
Ang mallotus oppositifolius sakop sa kahenera nga mallotus sa kabanay nga euphorbiaceae. Locally it is known as sroti in ewe or strataduca in akan burkill, 1985. Adsorption and inhibitive action of ethanol extracts of mallotus oppositifolius leaves for the corrosion of mild steel in 1m hydrochloric acid solution. Jun 19, 2019 the methanol leaf extract of mallotus oppositifolius was evaluated for anti inflammatory activity in rats and mice using acute and chronic antiinflammatory. The methanol leaf extract of mallotus oppositifolius was evaluated for. Diabetes which is associated with impaired glucose metabolism leads to oxidative stress which with an attendant protein glycation will produce free radicals 19. Scavenging activity of mallotus oppositifolius a kinetic study. Racemic compounds 1 and 2 were separated by chiralphase hplc, and the.
The structures of 15 were confirmed by nmr and mass analyses. All the other species are found in east asia, the indian subcontinent, southeast asia, eastern australia, and certain islands of the western pacific. Antidepressant effects of mallotus oppositifolius in acute. Mallotus oppositifolius can be coppiced and pollarded. The methanol leaf extract of mallotus oppositifolius was evaluated for antiinflammatory activity in rats and mice using acute and chronic antiinflammatory models with acetylsalicylate acid aspirin as the reference drug. Preliminary phytochemical screening conducted on the crude methanol and aqueous extracts of the plant revealed the presence of alkaloids, flavonoids, saponins, tannins, steroids, cardiac glycosides and terpenoids in both extracts of the plant. Mallotus oppositifolius pdf the methanol leaf extract of mallotus oppositifolius was evaluated for anti inflammatory activity in rats and mice using acute and chronic. Antiinflammatory and antioxidant activities of mallotus oppositifolius. Treepie is on kumkum tree or kamala tree mallotus philippensis. Thus the present study investigated the effect of the hydroalcoholic leaf extract of the plant in acute antidepressant modelsthe forced swim fst and tail suspension tests tst. Comparative chemotaxonomic studies on sroti mallotus. Oct 29, 2019 mallotus oppositifolius filed as glinus oppositifolius l. The mallotus oppositifolius nyanyafrowais one the oldest. Files are available under licenses specified on their description page.
Mallotus oppositifolius filed as glinus oppositifolius l. Mallotus oppositifolius is widely distributed and occurs from senegal east to ethiopia and south to angola and mozambique, and also in madagascar. Epub oct evaluation of mallotus oppositifolius methanol leaf extract on the. Euphorbiaceae is folklorically used to treat diabetic conditions in some parts of nigeria therefore the study, to investigate the extract of the leaves for activities on hyperglycaemia, lipid peroxidation, and increased cholesterol levels in vivo in alloxan diabetic rats as well as its potential antioxidant activity in vitro. Enter and press button then you will see the osd menu on the monitor. The herbal medicine, a leaf extract from the shrub mallotus oppositifolius, was previously found to be effective in controlling seizures but the mechanism was unknown. It has a short, and often fluted bole that can be up to 50cm in diameter, but is usually much less. Adongo 2 department of pharmacology, university of ghana medical school, college of health sciences, university of ghana, accra, ghana. The tropical genus mallotus, a member of the family euphorbiaceae, contains. The rats were fasted overnight before experimentation but were allowed free. It is known as the kamala tree or red kamala or kumkum tree, due to the fruit covering, which produces a red dye. Hydroalcoholic extract of leaves of mallotus oppositifolius moe, a plant used for cns conditions in ghana, was investigated for acute antidepressant effects in the forced swimming fst and tail suspension tests tst. Research article evaluation of mallotus oppositifolius methanol leaf extract on the glycaemia and lipid peroxidation in alloxaninduced diabetic rats. The mallotus oppositifolius nyanyafrowa is one of the oldest tree in the forest but its height and stature remains the same even after a thousand years.
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